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    Criterion of Therapeutic Effect:

    1. If HBV-DNA volume 1?104 cp/mL: 4/25 (16%)

    2. Lasting response:

    HBV-DNA volume 1?104 cp/mL: 2/25 (8%)

    Among the results of lasting response,

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    Research Method:

    Quantitative determination by contrasting HBV-DNA of cases before and after the treatment.

    Number of cases: 25 (n)

    Case Selection: Between the age of 16 and 65, in accordance with the diagnosis standards pf chronic Hepatitis B, with negative e antigen and positive e antibody, HBV-DNA > 1?104 cp/mL.

    Detection Method: All the blood samples are detected by Sichuan Clinical Detection Center; PCR-ELISA quantitative determination is used within detection range of 1?104 - 1?107-8, HBV-DNA, unit of measurement is cp/mL.

    Direction Plan: one suppository provided by Vigconic (International) Ltd. Bid. The course of treatment is six months, the tracing observation after withdrawal lasts six months.

    Observation index:

    1. HBV-DNA response after the treatment.

    2. Lasting HBV-DNA response (six months after withdrawal).

    Criterion of Therapeutic Effect:

    1. If HBV-DNA volume 1?104 cp/mL: 4/25 (16%)

    2. Lasting response:

    HBV-DNA volume 1?104 cp/mL: 2/25 (8%)

    Among the results of lasting response, 1

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    s standards pf chronic Hepatitis B, with negative e antigen and positive e antibody, HBV-DNA > 1?104 cp/mL.

    Detection Method: All the blood samples are detected by Sichuan Clinical Detection Center; PCR-ELISA quantitative determination is used within detection range of 1?104 - 1?107-8, HBV-DNA, unit of measurement is cp/mL.

    Direction Plan: one suppository provided by Vigconic (International) Ltd. Bid. The course of treatment is six months, the tracing observation after withdrawal lasts six months.

    Observation index:

    1. HBV-DNA response after the treatment.

    2. Lasting HBV-DNA response (six months after withdrawal).

    Criterion of Therapeutic Effect:

    1. If HBV-DNA volume 1?104 cp/mL: 4/25 (16%)

    2. Lasting response:

    HBV-DNA volume 1?104 cp/mL: 2/25 (8%)

    Among the results of lasting response,

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    determination is used within detection range of 1?104 - 1?107-8, HBV-DNA, unit of measurement is cp/mL.

    Direction Plan: one suppository provided by Vigconic (International) Ltd. Bid. The course of treatment is six months, the tracing observation after withdrawal lasts six months.

    Observation index:

    1. HBV-DNA response after the treatment.

    2. Lasting HBV-DNA response (six months after withdrawal).

    Criterion of Therapeutic Effect:

    1. If HBV-DNA volume 1?104 cp/mL: 4/25 (16%)

    2. Lasting response:

    HBV-DNA volume 1?104 cp/mL: 2/25 (8%)

    Among the results of lasting response,

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    the tracing observation after withdrawal lasts six months.

    Observation index:

    1. HBV-DNA response after the treatment.

    2. Lasting HBV-DNA response (six months after withdrawal).

    Criterion of Therapeutic Effect:

    1. If HBV-DNA volume 1?104 cp/mL: 4/25 (16%)

    2. Lasting response:

    HBV-DNA volume 1?104 cp/mL: 2/25 (8%)

    Among the results of lasting response,

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    Criterion of Therapeutic Effect:

    1. If HBV-DNA volume 1?104 cp/mL: 4/25 (16%)

    2. Lasting response:

    HBV-DNA volume 1?104 cp/mL: 2/25 (8%)

    Among the results of lasting response, 16 blood serum samples are detected through fluorimetric quantitative determination PCR by the instruments of PE.USD, H-7700 in the second attached hospital of Guangzhou Medical College. The result is in accordance with that in Sichuan Clinical Testing Center. (8 cases among it < 1?102 cp/mL). The testing range of this testing method is 1?102 - 1?107-8 cp/mL.

    Conclusion

    The reason for the repeatedly abnormal liver function of Chronic Hepatitis B (CHB) patients lies in the repeatedly duplication of HBV after infection, which leads to fibrosis of liver, then cirrhosis and liver cancer. It is commonly accepted that if CHB shows the transformation of HBeAg/Anti-HBe, HBV-DNA becoming negative, liver function returning to normal state, the disease is relieved.

    However, parts of patients with the transformation of HBeAg/Anti-HBe still remain positive in HBV-DNA and the pathological chang

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